We knew from previous studies that orexin stimulated physical activity.

‘We knew from previous studies that orexin stimulated physical activity, and so we wanted find out if there is activity more in lean rats increased in obese rats, said Kotz The. In into the lateral hypothalamus area of the brains of the two groups orexin and found that the lean rats was still active, while the obese rats respond is not much at all. ‘not only do the lean rats base base activity rate but more respond to orexin, ‘she said.

They found that the lean group moved significantly more during this baseline period than the obese group, Kotz said. This was, still active, rats were young and both groups weighed the same – eliminating the obesity itself as the cause of the decreased movement. After collecting baseline data, the researchers moved to the experimental part of the study. Lean rats increased expression of orexin receptors. (more…)

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